Home / Our Products / Promote Granulation / PROMOGRAN™ Matrix

Evidence

 

Evidence
type
Type Year of
publication
Author Title
Level one - RCT study Evidence summary 2007 Lázaro-Martinez, J.L. Randomized comparative trial of a collagen/oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers
Level one - RCT study Evidence summary 2005 Nisi, G. Use of a protease modulating matrix in the treatment of pressure sores
Level one - RCT study Article 2005 Wollina, U.,
et al.
Preliminary observations into the effects of a topical collagen-based matrix on wounds in patients with chronic venous leg ulcers.
Level one - RCT study Evidence summary 2002 Veves, A.,
et al.
A randomized controlled trial of PROMOGRAN  vs standard treatment in the management of diabetic foot ulcers
Level one - RCT study Article 2002 Vin, F.,
et al.
The healing properties of PROMOGRAN; in venous leg ulcers
Clinical Poster 2012 Cullen, B.,
et al.
Clinical outcomes with the early adoption of collagen/ORC dressings
Clinical Article 2010 Harding, K.,
et al.
Health Economics: utilizing advanced care wound products for clinical and cost effectiveness
Clinical/In vitro Poster 2009 Cullen, B.,
et al.
The effect of collagen-based wound dressings on bacterial growth
In vitro Poster

2013

Simmons, R., et al.

Effect of collagen/ORC/silver-ORC on bacterial proteases

In vitro Poster 2010 Cullen, B.,
et al.
Use of oxidized regenerated cellulose in facilitating wound healing
In vitro Poster 2007 Cullen, B.,
et al.
An in vitro evaluation of advanced wound dressings and the chronic wound environment
In vitro/ex vivo Poster 2010 Cullen, B.,
Silcock, D.
Collagen/Oxidized regenerated cellulose therapies in managing chronic wounds
Case study series Clinical 2013

 AA.VV.

Using PROMOGRAN/PROMOGRAN PRISMA in wounds with elevated protease activity: CASE STUDIES
Case study Poster   Reed, D. Combination therapy for full thickness wounds utilizing an ORC/collagen matrix dressing and negative pressure therapy
Product review Article 2010 Cullen, B.,
Ivins, S.
PROMOGRAN & PROMOGRAN PRISMA made easy

 In vitro

Article 2009 Gibson, D.,
et al.
MMPs made easy
Level one - RCT study Article 2008 Smeets, R. et al The effect of oxidised regenerated cellulose/collagen matrix in wound exudate of patients with chronic venous ulceration
Level one - RCT study Article 2007 Kakagia, D.D. et al. A prospective randomized trial of PROMOGRAN Matrix and autologous growth factors in diabetic foot ulcers.
Level one - RCT study Article 2011 Ulrich, D. et al The effect of oxidized regenerated cellulose/collagen matrix on wound exudate of patients with diabetic foot ulcers

Level one - RCT study

Article

2006

Lobmann, R. et al.

Diabetic foot wounds managed with an absorbent dressing.

Level one - RCT study

Article

2005

Wollina, U. et al.

Some effects of a topical collagen-based matrix on the microcirculation and wound healing

In vitro/ex vivo/clinical

Poster

2011

Cullen, B., Silcock, D.

Evidence for collagen/ORC therapies - in vitro, ex vivo and in clinical practice

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



















Further information:

The role of Proteases in wound healing
OWM Educational website on Proteases in Wound Care

 
Systagenix is not responsible for the content of external websites.


C4251 JAN 2015
PRB C1435

References

References

1. Nisi G. et al. Use of a protease-modulating matrix in the treatment of pressure sores. Chir Ital 2005, vol. 57(4):465-468.

2. Lazaro-Martinez, J. L. et al. Randomized comparative trial of a collagen/oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers. F.R. Circ. Esp. 2007, 82(1), 27-31.

3. Veves, A. et al. A Randomized, Controlled Trial of Promogran (a Collagen Oxidized Regenerated Cellulose Dressing) vs Standard Treatment in the Management of Diabetic Foot Ulcers. Arch. Surg 2002, vol. 137:822-827.

4. Vin, F. et al. The healing properties of Promogran in venous leg ulcers. J. Wound Care 2002; 11(9):335-41.

5. Lobmann, R. et al. Expression of matrix metalloproteinases and growth factors in diabetic foot wounds treated with a protease absorbent dressing. J Diabetes Complications 2006; 20(5): 329-335.

6. Ulrich, D. et al. Effect of oxidized regenerated cellulose/collagen matrix on proteases in wound exudate of patients with diabetic foot ulcers. J Wound Ostomy Continence Nurs. 2011 38(5) 1-7.

7. Smeets, R. et al. Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration. Int. Wound J. 2008, 5:195-203.

8. Kakagia, D.D. et al. Synergistic action of protease-modulating matrix and autologous growth factors in healing of diabetic foot ulcers. A prospective randomized trial. J Diabetes Complications 2007; 21(6): 387-91.
9. Hart , J. et al. The role of oxidized regenerated cellulose / collagen in wound repair: effects in vitro on fibroblast biology and in vivo in a model of compromised healing. Int J Biochem Cell Biol 2002;34:1557-1570.

10. Cullen, B. et al. Modulation of the chronic wound environment; an in vitro evaluation of advanced wound therapies Poster, SAWC 2007.

11. Cullen, B. et al. Collagen ORC rebalances the wound environment. Poster WHS, 2003.

12. Cullen, B. et al. Use of oxidized regenerated cellulose in facilitating wound healing. Poster, EWMA 2010.

13. Cullen B. et al. The role of oxidised regenerated cellulose/collagen in chronic wound repair and its potential mechanisms of action. Int J Biochem & Cell Biol 2002; 34: 1544-1556

14. Cullen B. et al. Mechanism of action of PROMOGRAN™, a protease modulating matrix, for the treatment of diabetic foot Ulcers. Presentation, EWMA 2008
15. Cullen, B. and Ivins, N. PROMOGRAN™ and PROMOGRAN PRISMA™ made easy. Wounds International 2010, Vol. 1(3)
16. Lanzara, S. and Zamboni, P. A pilot randomised trial to determine the effects of a new active dressing on wound healing of venous leg ulcers. Presentation, EWMA 2008.
17. Wollina, U. et al. Some Effects of a Topical Collagen-Based Matrix on the Microcirculation and Wound Healing in Patients with Chronic Venous Leg Ulcers: Preliminary Observations. Low Extr WOUNDS 2005, vol 4(4):214–224.
18. Lazaro Martinez, J.L et al. A Retrospective Analysis of the Cost-effectiveness of a Collagen/Oxidized Regenerated Cellulose Dressing in the Treatment of Neuropathic Diabetic Foot Ulcers. Ostomy Wound Management 2010; 55(11A):4-8.

Legal Notice Privacy Policy © Copyright 2016, 2018, KCI Licensing, Inc. All rights reserved.